Interleukin 18 -607 A/C Gene Polymorphism is Associated With Susceptibility to IgA Nephropathy in a Chinese Han Population.

doi:10.1097/PAI.0000000000000364

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Article

Interleukin 18 -607 A/C Gene Polymorphism is Associated With Susceptibility to IgA Nephropathy in a Chinese Han Population.

Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000

Yang Bin, Feng Weihua, Li Yi, Shi Yunying, Cai Bei, Liao Yun, Zhang Junlong, Huang Zhuochun, Wang Lanlan

Abstract excerpt

The association between a single-nucleotide polymorphism (SNP; -607A/C) in the promoter region of the IL-18 gene with IL-18 promoter transcription activity and the level of IL-18 protein production has been observed repeatedly. However, the association between the IL-18-607A/C (rs1946518) promoter polymorphism and IgA nephropathy (IgAN) in a Chinese Han population is still unclear. A total of 166 patients with...

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PMID: 27028244
DOI: 10.1097/PAI.0000000000000364

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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