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Mutations in lysX as the new and reliable markers for tuberculosis Beijing and modern Beijing strains.

Tuberculosis (Edinburgh, Scotland) - 1 Mar 2016

Zhao Li-li, Xiao Tong-yang, Sun Qing, Liu Hai-can, Zhao Xiu-qin, Jiang Yi, Li Gui-lian, Zeng Chun-yan, Wan Kang-lin

Abstract excerpt

Genotyping results and DNA sequencing analysis of 235 Mycobacterium tuberculosis (M. tuberculosis) isolates from China indicated that mutations at codon 995 (Pro CCG to Pro CCA) and 701 (Ile ATT to Thr ACT) in lysX gene (Rv1640c), are specific markers for Beijing and modern Beijing strains, respectively. This observation was also confirmed by 24 genomes of M. tuberculosis strains from other countries. Moreover, a...

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PMID: 26980493
DOI: 10.1016/j.tube.2015.12.006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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