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Article

Simple multiplex PCR assay for identification of Beijing family Mycobacterium tuberculosis isolates with a lineage-specific mutation in Rv0679c.

Journal of clinical microbiology - 1 Jul 2013

Nakajima Chie, Tamaru Aki, Rahim Zeaur, Poudel Ajay, Maharjan Bhagwan, Khin Saw Aye, Ling Hong, Hattori Toshio, Iwamoto Tomotada, Fukushima Yukari, Suzuki Haruka, Suzuki Yasuhiko, Matsuba Takashi

Abstract excerpt

The Beijing genotype of Mycobacterium tuberculosis is known to be a worldwide epidemic clade. It is suggested to be a possibly resistant clone against BCG vaccination and is also suggested to be highly pathogenic and prone to becoming drug resistant. Thus, monitoring the prevalence of this lineage seems to be important for the proper control of tuberculosis. The Rv0679c protein of M. tuberculosis has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 23596248
DOI: 10.1128/JCM.03404-12
PMCID: PMC3697683

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