Article
Genetic diversity of the Mycobacterium tuberculosis Beijing family based on IS6110, SNP, LSP and VNTR profiles from Thailand.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jul 2011
Faksri Kiatichai, Drobniewski Francis, Nikolayevskyy Vladyslav, Brown Timothy, Prammananan Therdsak, Palittapongarnpim Prasit, Prayoonwiwat Naraporn, Chaiprasert Angkana
Abstract excerpt
The Beijing family of Mycobacterium tuberculosis (MTB) has been shown to be highly virulent and is associated with tuberculosis outbreaks and drug resistance. To explore the evolutionary pathway of this genotype, 165 epidemiologically unlinked Beijing MTB isolates from Thailand were characterized based on IS6110, variable number of tandem repeats (VNTRs), region of differences (RDs) and single nucleotide...
Topics
- Gene Deletion
- Genetic Variation
- Genome, Bacterial
- Humans
- Mycobacterium tuberculosis
- Phylogeny
- Thailand
- Tuberculosis, Meningeal
- Tuberculosis, Pulmonary