Article
Phylogeny of Mycobacterium tuberculosis Beijing strains constructed from polymorphisms in genes involved in DNA replication, recombination and repair.
PloS one - 20 Jan 2011
Mestre Olga, Luo Tao, Dos Vultos Tiago, Kremer Kristin, Murray Alan, Namouchi Amine, Jackson Céline, Rauzier Jean, Bifani Pablo, Warren Rob, Rasolofo Voahangy, Mei Jian, Gao Qian, Gicquel Brigitte
Abstract excerpt
BACKGROUND: The Beijing family is a successful group of M. tuberculosis strains, often associated with drug resistance and widely distributed throughout the world. Polymorphic genetic markers have been used to type particular M. tuberculosis strains. We recently identified a group of polymorphic DNA repair replication and recombination (3R) genes. It was shown that evolution of M. tuberculosis complex strains can...
Topics
- DNA Repair
- DNA Replication
- DNA, Bacterial
- Genetic Phenomena
- Mycobacterium tuberculosis
- Phylogeny
- Polymorphism, Single Nucleotide
- Recombination, Genetic