Article
A novel method of identifying Mycobacterium tuberculosis Beijing strains by detecting SNPs in Rv0444c and Rv2629.
Current microbiology - 1 Mar 2014
Zhang Lu, Xu Wenxi, Cui Zhenling, Liu Yanyan, Wang Wenjie, Wang Jie, Hu Ding, Liu Dingqian, Wang Honghai
Abstract excerpt
A particular genotype of tuberculosis, named Beijing strain, is strongly associated with drug resistance and high virulence. Therefore, rapid prospective identification of Mycobacterium tuberculosis Beijing strains is very important for identifying and controlling tuberculosis of Beijing genotype. In the present study, we found that the co-mutation, A191C in Rv2629 and G243C in Rv0444c, is closely related to...
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