Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A morphological and immunophenotypic map of the immune response in Merkel cell carcinoma.

Human pathology - 1 Jun 2016

Walsh Noreen M, Fleming Kirsten E, Hanly John G, Dakin Hache Kelly, Doucette Steve, Ferrara Gerardo, Cerroni Lorenzo

Abstract excerpt

The susceptibility of Merkel cell carcinoma to the host immune response has prompted a search for effective immunotherapy. CD8-positive T lymphocytes are considered key effectors of this response, but the cellular infiltrates also harbor tumor-protective agents. By developing a comprehensive morphological and immunophenotypic map of tumor-infiltrating lymphocytes (TILS) in Merkel cell carcinoma, we aimed to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Merkel Cell
Share to CD8-Positive T-Lymphocytes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Immunotherapy

Share to Lymphocyte Count

Share to Lymphocytes, Tumor-Infiltrating

Share to T-Lymphocytes, Regulatory

Share to Tumor Escape

Share to Tumor Microenvironment

Source

Identifiers

PMID: 26980039
DOI: 10.1016/j.humpath.2016.02.002

Genes

FOXP3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A morphological and immunophenotypic map of the immune response in Merkel cell carcinoma.PMID 26980039Read ↗

Recent advances in the biology of Merkel cell carcinomaSemantic proximity Read ↗

Merkel cell carcinoma.Semantic proximity Read ↗

The presence of Merkel cell carcinoma polyomavirus is associated with a distinct phenotype in neoplastic Merkel cell carcinoma cells and their tissue microenvironment.Semantic proximity Read ↗

Reviewing the current evidence supporting early B-cells as the cellular origin of Merkel cell carcinomaSemantic proximity Read ↗

Spatially organized inflammatory myeloid-CD8 <sup>+</sup> T cell aggregates linked to Merkel-cell Polyomavirus driven Reorganization of the Tumor MicroenvironmentSemantic proximity Read ↗

Tumor-Infiltrating Merkel Cell Polyomavirus-Specific T Cells Are Diverse and Associated with Improved Patient Survival.Semantic proximity Read ↗

Current status of Merkel cell carcinoma: Epidemiology, pathogenesis and prognostic factorsSemantic proximity Read ↗

Characterization of the Impact of Merkel Cell Polyomavirus-Induced Interferon Signaling on Viral InfectionSemantic proximity Read ↗

Increased Detection of Merkel Cell Polyomavirus in Non-Melanoma Skin Cancer and Its Association with Host Immunogenetic ProfileSemantic proximity Read ↗

Merkel cell carcinoma: insights into pathogenesis.Semantic proximity Read ↗

Identifying the Target Cells and Mechanisms of Merkel Cell Polyomavirus InfectionSemantic proximity Read ↗

B cell responses specific for polyomavirus-derived oncoprotein are predictive of Merkel cell carcinoma tumor controlSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.