Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibition of Lipolysis Ameliorates Diabetic Phenotype in a Mouse Model of Obstructive Sleep Apnea.

American journal of respiratory cell and molecular biology - 1 Aug 2016

Weiszenstein Martin, Shimoda Larissa A, Koc Michal, Seda Ondrej, Polak Jan

Abstract excerpt

Obstructive sleep apnea (OSA) is associated with insulin resistance, glucose intolerance, and type 2 diabetes. Causal mechanisms mediating this association are not well defined; however, augmented lipolysis in adipose might be involved. Here, we investigated the effect of acipimox treatment (lipolysis inhibitor) on glucose tolerance and insulin sensitivity in mice exposed to intermittent hypoxia (IH). C57BL6/J...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adiposity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Mellitus, Experimental

Share to Fatty Acids

Share to Hypoxia

Share to Lipolysis

Share to Pyrazines

Share to Sleep Apnea, Obstructive

Source

Open in PubMed Open full text

Identifiers

PMID: 26978122
DOI: 10.1165/rcmb.2015-0315OC
PMCID: PMC4979366

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibition of Lipolysis Ameliorates Diabetic Phenotype in a Mouse Model of Obstructive Sleep Apnea.PMID 26978122Read ↗

Intermittent Hypoxia Drives Early Metabolic Dysfunction in Brown Adipose TissueSemantic proximity Read ↗

The lipolysis inhibitor acipimox reverses the cardiac phenotype induced by electronic cigarettes.Semantic proximity Read ↗

Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance DevelopmentSemantic proximity Read ↗

Activation of the Integrated Stress Response and Metabolic Dysfunction in a Murine Model of Sleep ApneaSemantic proximity Read ↗

Metformin protects the heart against chronic intermittent hypoxia through AMPK-dependent phosphorylation of HIF-1αSemantic proximity Read ↗

Intermittent Hypoxia and Weight Loss: Insights into the Etiology of the Sleep Apnea Phenotype.Semantic proximity Read ↗

IMPA2 Ameliorates High-Fat Diet-Induced Obesity by Enhancing Adaptive Thermogenesis in a Ca2+-activated Mitochondrial Biogenesis PathwaySemantic proximity Read ↗

Combined intermittent and sustained hypoxia is a novel and deleterious cardio-metabolic phenotype.Semantic proximity Read ↗

Comparison of Visceral Fat Lipolysis Adaptation to High-Intensity Interval Training in Obesity-Prone and Obesity-Resistant RatsSemantic proximity Read ↗

The Impact of Intermittent Hypoxia on Metabolism and CognitionSemantic proximity Read ↗

Endoplasmic reticulum stress may induce apoptosis in gastrocnemius injury of obese mice with OSAHSSemantic proximity Read ↗

The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-fat Diet-Induced Obesity in rat <i>via</i> Promoting Adipose LipolysisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.