Article
Intermittent Hypoxia Mediates Caveolae Disassembly That Parallels Insulin Resistance Development
26 Nov 2020
Abstract excerpt
Repetitive complete or incomplete pharyngeal collapses are leading to chronic intermittent hypoxia (CIH), a hallmark feature of obstructive sleep apnea (OSA) syndrome responsible for many metabolic disorders. In humans, an association between OSA and insulin resistance has been found independently of the degree of obesity. Based on our previous work showing that hypoxia applied to adipocytes led to cellular...
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