Article
Intermittent Hypoxia and Weight Loss: Insights into the Etiology of the Sleep Apnea Phenotype.
Advances in experimental medicine and biology - 1 Jan 2023
Gagnon Marianne, Fournier Stéphanie, Marcouiller François, Guay Loralie, Joseph Vincent, Michael Natalie J, Kinkead Richard
Abstract excerpt
Sleep apnea (SA) is a major respiratory disorder with increased risk for hypertension and obesity; however, our understanding of the origins of this complex disorder remains limited. Because apneas lead to recurrent drops in O2 during sleep, intermittent hypoxia (IH) is the main animal model to explore the pathophysiology of SA. Here, we assessed the impacts of IH on metabolic function and related signals. Adult...
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