Article

The Gene Knockout of Angiotensin II Type 1a Receptor Improves High-fat Diet-Induced Obesity in rat <i>via</i> Promoting Adipose Lipolysis

2022-04-07

Abstract excerpt

<h4>Aims</h4> The renin-angiotensin system (RAS) is over-activated and the serum angiotensin II (Ang II) level increased in obese patients, while their correlations were incompletely understood. This study aims to explore the role of Ang II in diet-induced obesity by focusing on adipose lipolysis. <h4>Methods</h4> Rat model of AT1aR gene knockout were established to investigate the special role of Ang II. Wild-t...

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Literature Corpus work: 02b9746c-3427-5da4-a9a1-eeb1ff27fcc0
DOI: 10.1101/2022.04.07.487533

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