Article
Possible Role of HLA-G, LILRB1 and KIR2DL4 Gene Polymorphisms in Spontaneous Miscarriage.
Archivum immunologiae et therapiae experimentalis - 1 Dec 2016
Nowak Izabela, Malinowski Andrzej, Barcz Ewa, Wilczyński Jacek R, Wagner Marta, Majorczyk Edyta, Motak-Pochrzęst Hanna, Banasik Małgorzata, Kuśnierczyk Piotr
Abstract excerpt
The KIR2DL4 receptor and its ligand HLA-G are considered important for fetal-maternal immune tolerance and successful pregnancy. The absence of a particular variant of KIR2DL4 might be a bad prognostic factor for pregnancy outcome. However, it could be compensated by the presence of the respective LILRB1 allele. Therefore, we investigated the KIR2DL4, LILRB1 and HLA-G polymorphisms in 277 couples with spontaneous...
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