Article
Significance of inhibitory maternal killer-cell immunoglobulin-like receptor (KIR) and fetal KIR ligand genotype combinations in placenta related obstetric complications.
Journal of reproductive immunology - 1 Nov 2021
Orgul Gokcen, Dalva Klara, Dalva-Aydemir Sevim, Alniacik Ridvan Goksel, Donmez Hanife Guler, Cakar Ayse Nur, Beksac Meral, Beksac Mehmet Sinan
Abstract excerpt
Some maternal killer-cell immunoglobulin-like receptor (KIR) and fetal KIR ligand genotypes are associated with obstetric complications, such as recurrent miscarriage, fetal growth restriction, preeclampsia, and preterm birth. However, how KIR/KIR ligand genotypes affect these placenta-related obstetric complications has not been fully understood. We aimed to demonstrate the association of maternal KIR-fetal KIR...
Topics
- Abortion, Habitual
- Adult
- Delivery, Obstetric
- Female
- Fetus
- Genotype
- HLA-C Antigens
- Humans
- Killer Cells, Natural
- Placenta
- Pre-Eclampsia
- Pregnancy
- Premature Birth