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Article

Highly Concordant Key Genetic Alterations in Primary Tumors and Matched Distant Metastases in Differentiated Thyroid Cancer.

Thyroid : official journal of the American Thyroid Association - 1 May 2016

Sohn Seo Young, Park Woong Yang, Shin Hyun Tae, Bae Joon Seol, Ki Chang Seok, Oh Young Lyun, Kim Sun Wook, Chung Jae Hoon

Abstract excerpt

BACKGROUND: Distant metastases uncommonly occur in differentiated thyroid carcinoma (DTC), but they are a frequent cause of thyroid cancer-related death. Genomic alterations in metastatic tumors, and the relationship with their corresponding primary tumors in DTC, are poorly understood. The objective of this study was to investigate whether genetic alterations in primary tumors are concordant with distant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26971368
DOI: 10.1089/thy.2015.0527

Genes

BRAF
TERT
NRAS
HRAS
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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