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Article

Risk Stratification Using a Novel Genetic Classifier Including PLEKHS1 Promoter Mutations for Differentiated Thyroid Cancer with Distant Metastasis.

Thyroid : official journal of the American Thyroid Association - 1 Nov 2020

Jung Chan Kwon, Jung Seung-Hyun, Jeon Sora, Jeong Young Mun, Kim Yourha, Lee Sohee, Bae Ja-Seong, Chung Yeun-Jun

Abstract excerpt

Background: Although most differentiated thyroid carcinomas (DTCs) have indolent behavior, DTCs with distant metastasis have a poor prognosis. However, there are no validated markers that predict the risk of distant metastasis and the prognosis of DTC. We aimed to develop a genetic classifier for predicting the outcomes of DTC patients with distant metastases. Methods: Targeted deep sequencing of 157...

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PMID: 32326836
DOI: 10.1089/thy.2019.0459

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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