Article
Genomic profiling of primary and metastatic thyroid cancers.
Endocrine-related cancer - 1 Feb 2024
Máximo Valdemar, Melo Miguel, Zhu Yingjie, Gazzo Andrea, Sobrinho Simões Manuel, Da Cruz Paula Arnaud, Soares Paula
Abstract excerpt
The genetic repertoire of primary thyroid cancers (TCs) is well documented, but there is a considerable lack of molecular profiling in metastatic TCs. Here, we retrieved and analyzed the molecular and clinical features of 475 primary and metastatic TCs subjected to targeted DNA sequencing, from the cBioPortal database. The cohort included primary and metastatic samples from 276 papillary thyroid carcinomas...
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