Article

High Concordance in Molecular Profiles Between Primary Tumors and Matched Lymph Node Metastases in Differentiated Thyroid Carcinoma: Implications for Clinical Sample Selection

2026-06-24

Abstract excerpt

<title>Abstract</title> <p> Genetic testing guides personalized management of differentiated thyroid carcinoma (DTC). However, tumor heterogeneity, including spatial and temporal heterogeneity, has created an unresolved clinical problem. It remains unclear whether molecular profile of the primary tumor (PT) can reliably reflect the genetic characteristics of paired lymph node metastases (LNM) to reduce redundant...

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Literature Corpus work: e3974f85-9308-5d09-9669-f106d95dbd34
DOI: 10.21203/rs.3.rs-9922971/v1

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