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Article

Long genes and genes with multiple splice variants are enriched in pathways linked to cancer and other multigenic diseases.

BMC genomics - 12 Mar 2016

Sahakyan Aleksandr B, Balasubramanian Shankar

Abstract excerpt

BACKGROUND: The role of random mutations and genetic errors in defining the etiology of cancer and other multigenic diseases has recently received much attention. With the view that complex genes should be particularly vulnerable to such events, here we explore the link between the simple properties of the human genes, such as transcript length, number of splice variants, exon/intron composition, and their...

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Identifiers

PMID: 26968808
DOI: 10.1186/s12864-016-2582-9
PMCID: PMC4788956

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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