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Article

Illumina error profiles: resolving fine-scale variation in metagenomic sequencing data.

BMC bioinformatics - 11 Mar 2016

Schirmer Melanie, D'Amore Rosalinda, Ijaz Umer Z, Hall Neil, Quince Christopher

Abstract excerpt

BACKGROUND: Illumina's sequencing platforms are currently the most utilised sequencing systems worldwide. The technology has rapidly evolved over recent years and provides high throughput at low costs with increasing read-lengths and true paired-end reads. However, data from any sequencing technology contains noise and our understanding of the peculiarities and sequencing errors encountered in Illumina data has...

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PMID: 26968756
DOI: 10.1186/s12859-016-0976-y
PMCID: PMC4787001

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