Article
GemSIM: general, error-model based simulator of next-generation sequencing data.
BMC genomics - 15 Feb 2012
McElroy Kerensa E, Luciani Fabio, Thomas Torsten
Abstract excerpt
BACKGROUND: GemSIM, or General Error-Model based SIMulator, is a next-generation sequencing simulator capable of generating single or paired-end reads for any sequencing technology compatible with the generic formats SAM and FASTQ (including Illumina and Roche/454). GemSIM creates and uses empirically derived, sequence-context based error models to realistically emulate individual sequencing runs and/or...
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