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Article

ADEPT, a dynamic next generation sequencing data error-detection program with trimming.

BMC bioinformatics - 29 Feb 2016

Feng Shihai, Lo Chien-Chi, Li Po-E, Chain Patrick S G

Abstract excerpt

BACKGROUND: Illumina is the most widely used next generation sequencing technology and produces millions of short reads that contain errors. These sequencing errors constitute a major problem in applications such as de novo genome assembly, metagenomics analysis and single nucleotide polymorphism discovery. RESULTS: In this study, we present ADEPT, a dynamic error detection method, based on the quality scores of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26928302
DOI: 10.1186/s12859-016-0967-z
PMCID: PMC4772517

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