Article
Characterization of sequence-specific errors in various next-generation sequencing systems.
Molecular bioSystems - 1 Mar 2016
Shin Sunguk, Park Joonhong
Abstract excerpt
Next-generation sequencing (NGS) is a popular method for assessing the molecular diversity of microbial communities without cultivation, for identifying polymorphisms in populations, and for comparing genomes and transcriptomes. However, sequence-specific errors (SSEs) by NGS systems can result in genome mis-assembly, overestimation of diversity in microbial community analyses, and false polymorphism discovery....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
