Article
NGS-eval: NGS Error analysis and novel sequence VAriant detection tooL.
Nucleic acids research - 1 Jul 2015
May Ali, Abeln Sanne, Buijs Mark J, Heringa Jaap, Crielaard Wim, Brandt Bernd W
Abstract excerpt
Massively parallel sequencing of microbial genetic markers (MGMs) is used to uncover the species composition in a multitude of ecological niches. These sequencing runs often contain a sample with known composition that can be used to evaluate the sequencing quality or to detect novel sequence variants. With NGS-eval, the reads from such (mock) samples can be used to (i) explore the differences between the reads...
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