Article
Effect of single-nucleotide polymorphisms in TRPV1 on burning pain and capsaicin sensitivity in Japanese adults.
Molecular pain - 1 Jan 2000
Okamoto Nozomu, Okumura Masayo, Tadokoro Osamu, Sogawa Norio, Tomida Mihoko, Kondo Eiji
Abstract excerpt
Transient receptor potential vanilloid 1 (TRPV1) is a nonselective cation channel that is expressed in the sensory neurons and responds to various noxious stimuli including heat and capsaicin. The molecular properties of TRPV1 have been clearly examined; however, there are obvious individual differences in human sensitivity to thermal stimuli and capsaicin. Here, we examined the possibility that different genome...
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