Article
Comparative genomics analysis of mononuclear phagocyte subsets confirms homology between lymphoid tissue-resident and dermal XCR1(+) DCs in mouse and human and distinguishes them from Langerhans cells.
Journal of immunological methods - 1 May 2016
Carpentier Sabrina, Vu Manh Thien-Phong, Chelbi Rabie, Henri Sandrine, Malissen Bernard, Haniffa Muzlifah, Ginhoux Florent, Dalod Marc
Abstract excerpt
Dendritic cells (DC) are mononuclear phagocytes which exhibit a branching (dendritic) morphology and excel at naïve T cell activation. DC encompass several subsets initially identified by their expression of cell surface molecules and later shown to possess distinct functions. DC subset differentiation is orchestrated by transcription factors, growth factors and cytokines. Identifying DC subsets is challenging as...
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