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Article

High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization.

Immunity - 19 Dec 2017

Alcántara-Hernández Marcela, Leylek Rebecca, Wagar Lisa E, Engleman Edgar G, Keler Tibor, Marinkovich M Peter, Davis Mark M, Nolan Garry P, Idoyaga Juliana

Abstract excerpt

Given the limited efficacy of clinical approaches that rely on ex vivo generated dendritic cells (DCs), it is imperative to design strategies that harness specialized DC subsets in situ. This requires delineating the expression of surface markers by DC subsets among individuals and tissues. Here, we performed a multiparametric phenotypic characterization and unbiased analysis of human DC subsets in blood, tonsil,...

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Identifiers

PMID: 29221729
DOI: 10.1016/j.immuni.2017.11.001
PMCID: PMC5738280

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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