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Article

High frequency of TERT promoter mutation in small cell carcinoma of bladder, but not in small cell carcinoma of other origins.

Journal of hematology & oncology - 20 Jul 2014

Zheng Xiaoyong, Zhuge Jian, Bezerra Stephania M, Faraj Sheila F, Munari Enrico, Fallon John T, Yang Ximing J, Argani Pedram, Netto George J, Zhong Minghao

Abstract excerpt

TERT promoter mutations were recently discovered in melanoma by next generation sequencing. Subsequently, several malignancies including urothelial carcinoma were also found to be associated with the same TERT promoter mutations. Small cell carcinoma (SCC) of the urinary bladder is a rare subtype with an aggressive clinical course. Despite the frequent occurrence of TERT promoter mutations in urothelial...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Small Cell

Share to Carcinoma, Transitional Cell

Share to Promoter Regions, Genetic

Share to Reverse Transcriptase Polymerase Chain Reaction

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Share to Urinary Bladder Neoplasms

Source

Open in PubMed Open full text

Identifiers

PMID: 25042800
DOI: 10.1186/s13045-014-0047-7
PMCID: PMC4223615

Genes

TERT

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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