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[Progress in the tumorigenic potential of iPSCs and methods to reduce it].

Sheng wu gong cheng xue bao = Chinese journal of biotechnology - 1 Sept 2015

Zhang Liping, Yang Guanheng, Zhang Jingzhi

Abstract excerpt

Since Yamanaka successfully reprogrammed murine fibroblasts into iPSCs in 2006, iPSCs technology has drawn much attention worldwide. Although iPSCs provides tremendous possibilities for both basic research and regenerative medicine, it has meanwhile potential risks, e.g. tumorigenicity. Scientists, therefore, have made efforts in clarifying the mechanism of the cause for iPSCs tumorigenicity and the way how to...

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PMID: 26955706

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