Article
Safety and efficacy of embryonic stem cell microenvironment in a leukemia mouse model.
Stem cells and development - 1 Aug 2014
Zhou Chenjing, Huang Zheqian, Li Panlong, Li Weiqiang, Liu Ying, Li Chaoyang, Liu Zhao, Wang Xiaoran, Wan Pengxia, Wang Zhichong
Abstract excerpt
The embryonic stem cell (ESC) microenvironment can promote the proliferation of terminal cells and reduce the invasiveness of tumor cells. However, implanting ESCs directly in vivo can result in tumorigenicity, immune rejection after differentiation, and graft-versus-host reaction. Therefore, saf...
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