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Article

Preprocessing and downstream analysis of microarray DNA copy number profiles

19 Feb 2010

Abstract excerpt

Analysis of DNA copy number profiles requires methods tailored to the specific nature of these data. The number of available data analysis methods has grown enormously in the last 5 years. We discuss the typical characteristics of DNA copy number data, as measured by microarray technology and review the extensive literature on preprocessing methods such as segmentation and calling. Subsequently, the focus narrows...

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PMID: 20172948
DOI: 10.1093/bib/bbq004

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