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Article

Dual nuclease activity of a Cas2 protein in CRISPR –Cas subtype I‐B of Leptospira interrogans

7 Mar 2016

Abstract excerpt

Leptospira interrogans serovar Copenhageni strain Fiocruz L1-130 carries a set of cas genes associated with CRISPR-Cas subtype I-B. Herein, we report for the first time active transcription of a set of cas genes (cas1 to cas8) of L. interrogans where cas4, cas1, cas2 and cas6, cas3, cas8, cas7, cas5 are clustered together in two independent operons. As an initial step toward comprehensive understanding of...

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PMID: 26950513
DOI: 10.1002/1873-3468.12124

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