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Testing S. sonnei GMMA with and without Aluminium Salt-Based Adjuvants in Animal Models

22 Apr 2024

Abstract excerpt

Shigellosis is one of the leading causes of diarrheal disease in low- and middle-income countries, particularly in young children, and is more often associated with antimicrobial resistance. Therefore, a preventive vaccine against shigellosis is an urgent medical need. We have proposed Generalised Modules for Membrane Antigens (GMMA) as an innovative delivery system for Shigella sonnei O-antigen, and an...

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PMID: 38675229
DOI: 10.3390/pharmaceutics16040568

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