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Article

Vaccine efficacy of transcutaneous immunization with amyloid β using a dissolving microneedle array in a mouse model of Alzheimer's disease.

Journal of neuroimmunology - 15 Jan 2014

Matsuo Kazuhiko, Okamoto Hideaki, Kawai Yasuaki, Quan Ying-Shu, Kamiyama Fumio, Hirobe Sachiko, Okada Naoki, Nakagawa Shinsaku

Abstract excerpt

Vaccine therapy for Alzheimer's disease (AD) based on the amyloid cascade hypothesis has recently attracted attention for treating AD. Injectable immunization using amyloid β peptide (Aβ) comprising 1-42 amino-acid residues (Aβ1-42) as antigens showed therapeutic efficacy in mice; however, the cl...

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Identifiers

PMID: 24315156
DOI: 10.1016/j.jneuroim.2013.11.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24315156-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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