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Article

Cell autonomous and nonautonomous requirements for Delltalike1 during early mouse retinal neurogenesis.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 2016

Riesenberg Amy N, Brown Nadean L

Abstract excerpt

BACKGROUND: In the vertebrate retina, six neuronal and one glial cell class are produced from a common progenitor pool. During neurogenesis, adjacent retinal cells use Notch signaling to maintain a pool of progenitors by blocking particular cells from differentiating prematurely. In mice there are multiple Notch pathway ligands and receptors, but the role(s) of each paralogue during retinal histogenesis remains...

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PMID: 26947267
DOI: 10.1002/dvdy.24402
PMCID: PMC4873400

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