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Article

Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Oct 2013

Mizeracka Karolina, Trimarchi Jeffrey M, Stadler Michael B, Cepko Constance L

Abstract excerpt

BACKGROUND: The vertebrate retina comprises sensory neurons, the photoreceptors, as well as many other types of neurons and one type of glial cell. These cells are generated by multipotent and restricted retinal progenitor cells (RPCs), which express Notch1. Loss of Notch1 in RPCs late during retinal development results in the overproduction of rod photoreceptors at the expense of interneurons and glia. RESULTS:...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 23813500
DOI: 10.1002/dvdy.24006
PMCID: PMC3882027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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