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Article

GDF11 controls the timing of progenitor cell competence in developing retina.

Science (New York, N.Y.) - 24 Jun 2005

Kim Joon, Wu Hsiao-Huei, Lander Arthur D, Lyons Karen M, Matzuk Martin M, Calof Anne L

Abstract excerpt

The orderly generation of cell types in the developing retina is thought to be regulated by changes in the competence of multipotent progenitors. Here, we show that a secreted factor, growth and differentiation factor 11 (GDF11), controls the numbers of retinal ganglion cells (RGCs), as well as a...

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Source

Identifiers

PMID: 15976303
DOI: 10.1126/science.1110175

Genes

GDF11

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-15976303-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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