Article
Melatonin Pathway and Atenolol-Related Glucose Dysregulation: Is There a Correlation?
Clinical and translational science - 1 Apr 2016
Chang S W, Gong Y, McDonough C W, Langaee T Y, Nasiri Kenari N, Beitelshees A L, Gums J G, Chapman A B, Turner S T, Johnson J A, Cooper-DeHoff R M
Abstract excerpt
Lower melatonin level, melatonin receptor gene variations, and atenolol treatment are associated with glucose dysregulation. We investigated whether atenolol-related glucose and melatonin changes are correlated, and whether single nucleotide polymorphisms (SNPs) in melatonin candidate genes contribute to interindividual variation in glucose change. Hypertensive Caucasians (n = 232) from the Pharmacogenomic...
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