Article
Genetics of melatonin receptor type 2 is associated with left ventricular function in hypertensive patients treated according to guidelines.
European journal of internal medicine - 1 Oct 2013
Huber Matthias, Treszl Andras, Reibis Rona, Teichmann Christopher, Zergibel Irina, Bolbrinker Juliane, Scholze Jürgen, Wegscheider Karl, Völler Heinz, Kreutz Reinhold
Abstract excerpt
BACKGROUND: Melatonin exerts multiple biological effects with potential impact on human diseases. This is underscored by genetic studies that demonstrated associations between melatonin receptor type 2 gene (MTNR1B) polymorphisms and characteristics of type 2 diabetes. We set out to test the hypothesis whether genetic variants at MTNR1B are also relevant for other disease phenotypes within the cardiovascular...
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