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Organelle Cooperation in Stem Cell Fate: Lysosomes as Emerging Regulators of Cell Identity

7 Jul 2020

Abstract excerpt

Regulation of stem cell fate is best understood at the level of gene and protein regulatory networks, though it is now clear that multiple cellular organelles also have critical impacts. A growing appreciation for the functional interconnectedness of organelles suggests that an orchestration of integrated biological networks functions to drive stem cell fate decisions and regulate metabolism. Metabolic signaling...

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PMID: 32733892
DOI: 10.3389/fcell.2020.00591

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