Article

Estrogen-Related Receptor is Required in Adult Drosophila Females for Germline Stem Cell Maintenance

2025-01-29

Abstract excerpt

Stem cell self-renewal and proper tissue function rely on conserved metabolic regulators to balance energy production with inter-organ metabolic trafficking. The estrogen-related receptor (ERR) subfamily of orphan nuclear receptors are major transcriptional regulators of metabolism. In mammals, ERRs have roles in regulating mitochondrial biosynthesis, lipid metabolism, as well as stem cell maintenance. The sole Dr...

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Literature Corpus work: 0d08a2f0-fa11-53e8-b474-b0ad4dca7d01
DOI: 10.1101/2025.01.29.635514

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