Association of gene expression and methylation of UQCRC1 to the predisposition of Alzheimer's disease in a Chinese population.

Abstract excerpt

DNA methylation is an important epigenetic mechanism for gene regulation and it is well established there is association between aging and DNA methylation. Alzheimer's disease (AD) is the most common neurodegenerative disease, characterized by amyloid plaque deposition and formation of neurofibrillary tangles. In this study, we examined the correlation between DNA methylation and gene expression of seven genes...

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