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Article

Association of RFC1 A80G and MTHFR C677T polymorphisms with Alzheimer's disease.

Neurobiology of aging - 1 Oct 2009

Bi Xiu-Hua, Zhao Hua-Lu, Zhang Zhen-Xin, Zhang Jun-Wu

Abstract excerpt

We examined polymorphisms in reduced folate carrier gene (RFC1) and methylenetetrahydrofolate reductase gene (MTHFR) for association with sporadic AD (SAD) in Chinese population. Significant associations of RFC1 A80G G allele and GG genotype with SAD (p=0.008, OR=1.312, 95%CI=1.072-1.605, and p=0...

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Source

Identifiers

PMID: 18258338
DOI: 10.1016/j.neurobiolaging.2007.12.010

Genes

MTHFR
RFC1
APOE

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18258338-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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