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MEF2C mRNA expression and cognitive function in Japanese patients with Alzheimer's disease

7 Nov 2017

Abstract excerpt

AIM: Despite continuing research into Alzheimer's disease (AD), its pathological mechanisms and modulating factors remain unknown. Several genes influence AD pathogenesis by affecting inflammatory pathways. Myocyte-enhancer factor 2C (MEF2C) is one such candidate gene for AD. METHODS: We examined MEF2C mRNA expression levels and methylation rates of CpG on its promoter region in peripheral leukocytes from...

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PMID: 29112298
DOI: 10.1111/pcn.12618

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