Article
Evolutionary dynamics of viral escape under antibodies stress: A biophysical model.
Protein science : a publication of the Protein Society - 1 Jul 2016
Chéron Nicolas, Serohijos Adrian W R, Choi Jeong-Mo, Shakhnovich Eugene I
Abstract excerpt
Viruses constantly face the selection pressure of antibodies, either from innate immune response of the host or from administered antibodies for treatment. We explore the interplay between the biophysical properties of viral proteins and the population and demographic variables in the viral escape. The demographic and population genetics aspect of the viral escape have been explored before; however one important...
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