Article
Evolutionary dynamics of escape from biomedical intervention.
Proceedings. Biological sciences - 22 Dec 2003
Iwasa Yoh, Michor Franziska, Nowak Martin A
Abstract excerpt
Viruses, bacteria, eukaryotic parasites, cancer cells, agricultural pests and other inconvenient animates have an unfortunate tendency to escape from selection pressures that are meant to control them. Chemotherapy, anti-viral drugs or antibiotics fail because their targets do not hold still, but evolve resistance. A major problem in developing vaccines is that microbes evolve and escape from immune responses....
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