Article
Approaches to Investigating Complex Genetic Traits in a Large-Scale Inbred Mouse Aging Study.
Veterinary pathology - 1 Mar 2016
Sundberg J P, Berndt A, Sundberg B A, Silva K A, Kennedy V, Smith R S, Cooper T K, Schofield P N
Abstract excerpt
Inbred mice are a unique model system for studying aging because of the genetic homogeneity within inbred strains, the short life span of mice relative to humans, and the rich array of analytic tools that are available. A large-scale aging study was conducted on 28 inbred strains representing great genetic diversity to determine, via histopathology, the type and diversity of spontaneous diseases that aging mice...
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