Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice.

Disease models & mechanisms - 1 Jan 2012

Schofield Paul N, Vogel Peter, Gkoutos Georgios V, Sundberg John P

Abstract excerpt

Recent advances in gene knockout techniques and the in vivo analysis of mutant mice, together with the advent of large-scale projects for systematic mouse mutagenesis and genome-wide phenotyping, have allowed the creation of platforms for the most complete and systematic analysis of gene function ever undertaken in a vertebrate. The development of high-throughput phenotyping pipelines for these and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Discovery
Share to Genome
Share to High-Throughput Screening Assays

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mice, Mutant Strains

Share to Phenotype

Source

Open in PubMed Open full text

Identifiers

PMID: 22028326
DOI: 10.1242/dmm.008334
PMCID: PMC3255539

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Exploring the elephant: histopathology in high-throughput phenotyping of mutant mice.PMID 22028326Read ↗

Histopathology reveals correlative and unique phenotypes in a high-throughput mouse phenotyping screen.Semantic proximity Read ↗

The International Mouse Phenotyping Consortium: comprehensive knockout phenotyping underpinning the study of human disease.Semantic proximity Read ↗

Excavating the Genome: Large-Scale Mutagenesis Screening for the Discovery of New Mouse Models.Semantic proximity Read ↗

Pathologic phenotyping of mutant mice.Semantic proximity Read ↗

Cause and effect considerations in diagnostic pathology and pathology phenotyping of genetically engineered mice (GEM).Semantic proximity Read ↗

High-throughput mouse phenotyping.Semantic proximity Read ↗

Commentary: The International Mouse Phenotyping Consortium: high-throughput in vivo functional annotation of the mammalian genome.Semantic proximity Read ↗

The International Mouse Phenotyping Consortium: past and future perspectives on mouse phenotyping.Semantic proximity Read ↗

High-throughput discovery of novel developmental phenotypes.Semantic proximity Read ↗

High-throughput gene knockouts and phenotyping in mice.Semantic proximity Read ↗

Large-scale mouse knockouts and phenotypes.Semantic proximity Read ↗

Mouse phenotyping sheds light on rare disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.