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Article

Differentiating inbred mouse strains from each other and those with single gene mutations using hair proteomics.

PloS one - 1 Jan 2012

Rice Robert H, Bradshaw Katie M, Durbin-Johnson Blythe P, Rocke David M, Eigenheer Richard A, Phinney Brett S, Sundberg John P

Abstract excerpt

Mutant laboratory mice with distinctive hair phenotypes are useful for identifying genes responsible for hair diseases. The work presented here demonstrates that shotgun proteomic profiling can distinguish hair shafts from different inbred mouse strains. For this purpose, analyzing the total hair shaft provided better discrimination than analyzing the isolated solubilized and particulate (cross-linked) fractions....

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Identifiers

PMID: 23251662
DOI: 10.1371/journal.pone.0051956
PMCID: PMC3522583

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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