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Article

A pharmacogenetic investigation of intravenous furosemide in decompensated heart failure: a meta-analysis of three clinical trials.

The pharmacogenomics journal - 1 Mar 2017

de Denus S, Rouleau J L, Mann D L, Huggins G S, Cappola T P, Shah S H, Keleti J, Zada Y F, Provost S, Bardhadi A, Phillips M S, Normand V, Mongrain I, Dubé M-P

Abstract excerpt

We conducted a meta-analysis of pharmacogenomic substudies of three randomized trials conducted in patients with decompensated heart failure (HF) that were led by National Heart Lung and Blood Institute (NHLBI)-funded HF Network to test the hypothesis that candidate genes modulate net fluid loss and weight change in patients with decompensated HF treated with a furosemide-based diuretic regimen. Although none of...

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Identifiers

PMID: 26927285
DOI: 10.1038/tpj.2016.4
PMCID: PMC5009007

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ABCC4
APOL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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