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Immune-Related Gene Polymorphisms and Pharmacogenetic Studies in Nephrology.

Clinical therapeutics - 1 Dec 2021

Tziastoudi Maria, Cholevas Christos, Stefanidis Ioannis, Theoharides Theoharis C

Abstract excerpt

A large subgroup of patients with chronic kidney disease still encounter serious adverse effects and lack of responsiveness to medications, possibly because of the interindividual genetic variability in genes involved in the metabolism and transport of the treatments used. As a consequence, several pharmacogenetic studies have been conducted in nephrology patients that examine the effect of genetic variants in...

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PMID: 34740465
DOI: 10.1016/j.clinthera.2021.09.020

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